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DR ANTHONY MELVIN CRASTO, WORLDDRUGTRACKER

Silence Starts Phase Ia/IIb Trial of Cancer Drug as It Looks to Balance Pipeline

 cancer  Comments Off on Silence Starts Phase Ia/IIb Trial of Cancer Drug as It Looks to Balance Pipeline
May 302013
 

Silence Starts Phase Ia/IIb Trial of Cancer Drug as It Looks to Balance Pipeline

Silence Starts Phase Ia/IIb Trial of Cancer Drug as It Looks to Balance Pipeline GenomeWeb If no toxicity is observed, the phase IIa arm of the trial will begin with pancreatic cancer patients receiving the two drugs once a week for three consecutive weeks, with no treatment on the fourth week. This dosing schedule will continue in … http://www.genomeweb.com/rnai/silence-starts-phase-iaiib-trial-cancer-drug-it-looks-balance-pipeline

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Iclusig (ponatinib) VERSUS Gleevec (imatinib)

 drugs  Comments Off on Iclusig (ponatinib) VERSUS Gleevec (imatinib)
May 302013
 

3 Innovative Biotech Companies With Promising Cancer Therapies
Seeking Alpha
The global, Phase III EPIC trial which compares Iclusig to Novartis’ blockbuster drug Gleevec (imatinib) in patients with newly diagnosed CML, is advancing. The company expects to reach full patient enrollment in the fourth quarter of 2013

http://seekingalpha.com/article/1467241-3-innovative-biotech-companies-with-promising-cancer-therapies?source=google_news

 

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May 292013
 

 

3 Biopharma Runners With Fuel in the Tank
Investorplace.com
Gilead Sciences (GILD) stock recently set a new all-time high after reporting that in a recent Phase 2 study, its oral drug idelalisib successfully drove the life-threatening chronic lymphocytic leukemia (CLL) into remission. The regimen produced a 97%

 

Gilead Sciences (GILD) stock recently set a new all-time high after reporting that in a recent Phase 2 study, its oral drug idelalisib successfully drove the life-threatening chronic lymphocytic leukemia (CLL) into remission. The regimen produced a 97% response rate, with 93% of trial patients surviving progression-free at the end of two years. CLL, which produces too many mature white cells, is the second most common form of leukemia in the U.S.

http://investorplace.com/2013/05/3-biopharma-runners-with-fuel-in-the-tank/

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Researchers identify novel class of drugs for prostate cancers

 Uncategorized  Comments Off on Researchers identify novel class of drugs for prostate cancers
May 292013
 

Photo of Dr. Ganesh Raj, an associate professor of urology at UT Southwestern Medical Center.

http://www.sciencecodex.com/researchers_identify_novel_class_of_drugs_for_prostate_cancers-112935

(Photo Credit: UT Southwestern Medical Center)

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Omthera Fish-Oil Drug Hooks AstraZeneca in $323M Buyout

 drugs  Comments Off on Omthera Fish-Oil Drug Hooks AstraZeneca in $323M Buyout
May 292013
 

AstraZeneca plc’s planned buyout of Omthera Pharmaceuticals Inc. to gain Phase III-validated Epanova, the anti-triglyceride therapy based on ultra-pure fish oil, puts the firm at a “distinct commercial advantage” over Amarin Corp. plc, with its recently launched Vascepa (icosapent ethyl), said Decision Resources (DR) analyst Paramjit Narang.

http://www.bioworld.com/content/omthera-fish-oil-drug-hooks-astrazeneca-323m-buyout-0

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Bristol Myers Squibb Co.present data on its Phase 3 drug nivolumab, which is closest to reaching the market. (Its FDA approval is expected in late 2014 or early 2015.)

 Phase 3 drug  Comments Off on Bristol Myers Squibb Co.present data on its Phase 3 drug nivolumab, which is closest to reaching the market. (Its FDA approval is expected in late 2014 or early 2015.)
May 292013
 

Bristol Myers Squibb Co. (BMY), Gilead Sciences, Inc. (GILD), Halozyme
Insider Monkey (blog)
present data on its Phase 3 drug nivolumab, which is closest to reaching the market. (Its FDA approval is expected in late 2014 or early 2015.) Nivolumab has the potential to treat a vast array of cancers. At ASCO, Bristol Myers Squibb Co.

http://www.insidermonkey.com/blog/bristol-myers-squibb-co-bmy-gilead-sciences-inc-gild-halozyme-therapeutics-inc-halo-3-stocks-to-watch-ahead-of-asco-152583/

 

Bristol Myers Squibb Co. (NYSE:BMY) present data on its Phase 3 drug nivolumab, which is closest to reaching the market. (Its FDA approval is expected in late 2014 or early 2015.)

Nivolumab has the potential to treat a vast array of cancers. At ASCO, Bristol Myers Squibb Co. (NYSE:BMY) will be presenting data for a Phase 1 study of nivolumad combined with Yervoy to treat melanoma. In a 52-patient study, patients with advanced melanoma saw an overall tumor shrinkage rate of 40%.

However, the company’s most advanced study with nivolumab is in treating advanced non-small cell lung cancer. There, it produced an overall survival of 9.6 months, which is 30% better than standard-of-care. It’s also produced a 22-month overall survival rate in patients with advanced kidney cancer; compared to 20 months for the current standard of care

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May 282013
 

Slowing the aging process -- only with antibiotics

EPFL scientists have revealed the mechanism, hidden deep within cell mitochondria, that is responsible for making organisms age. Nematodes treated with antibiotics designed to disrupt this mechanism lived longer and healthier lives.

(Photo Credit: EPFLnews)

Slowing the aging process using only antibiotics 

 

READ ALL AT

http://www.kurzweilai.net/slowing-the-aging-process-using-only-antibiotics?utm_source=KurzweilAI+Daily+Newsletter&utm_campaign=b2bfdefdba-UA-946742-1&utm_medium=email&utm_term=0_6de721fb33-b2bfdefdba-282116853

Why is it that within a homogeneous population of the same species, some individuals live three times as long as others? EPFL researchers investigated this question and found the mechanism responsible for aging hidden deep within mitochondria. The were able to dramatically slow aging down in worms by administering antibiotics to the young, achieving a … more…
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Merrimack-completes-patient-enrollment-in-phase-2-breast-cancer-study

 drugs  Comments Off on Merrimack-completes-patient-enrollment-in-phase-2-breast-cancer-study
May 282013
 

read all at

http://clinicaltrials.pharmaceutical-business-review.com/news/merrimack-completes-patient-enrollment-in-phase-2-breast-cancer-study-240513

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Diabetes Drug To Be Sold As Weight Loss Medication Liraglutide (Victoza),

 drugs  Comments Off on Diabetes Drug To Be Sold As Weight Loss Medication Liraglutide (Victoza),
May 282013
 

File:Liraglutide structure.svg

liraglutide

Read all at Links

 

http://www.medicaldaily.com/articles/15910/20130526/diabetes-drug-sold-weight-loss-medication.htm

Danish pharmaceutical company Novo Nordisk announced plans to re-brand and sell its diabetes drug liraglutide (Victoza) as a weight loss drug for obese people by 2015. Currently, the drug is approved and sold to help regulate insulin production in people living with type 2 diabetes.

 

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