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p-Anisaldehyde, or 4-methoxybenzaldehyde. NMR

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Jul 042014

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p-anisaldehyde, or 4-methoxybenzaldehyde.

(C₈H₈O₂)

This ¹³C spectrum exhibits resonances at the following chemical shifts, and with the multiplicity indicated:

Shift (ppm)
190.8	130.2
154.6	114.5
132.0	55.4

55.4……….. -0CH3

114.5………TWO AROM -CH ORTHO TO O ATOM

130.2……..AROM C OF -CHO

132……….TWO AROM -CH ORTHO TO -CHO

154.6……….AROM C OF -OGP

190.8……. CH=O GP

1H NMR

FIRST SIGNAL IS 3H OF CH3

SECOND IS DOUBLET OF TWO H OF AROM RING ORTHO TO O ATOM

THIRD IS DOUBLET OF TWO H OF AROM RING ORTHO TO -CHO GP

LAST IS LONE H OF CHO

IR

ANTHONY MELVIN CRASTO

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Renewed focus on dementia checked by drug challenges

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Jul 042014

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Efforts to target amyloid protein plaques, thought to be responsible for Alzheimer’s disease, have run into trouble © Science Photo Library

The world needs to tackle head-on the market failures undermining dementia research and drug development, UK Prime Minister David Cameron told a summit of world health and finance leaders in London in June. He announced an investigation into how to get medicines to patients earlier, extend patents and facilitate research collaborations, to report this autumn. But just how much difference will these sorts of measures make when scientists are still grappling with exactly what causes different types of dementia?

Renewed focus on dementia checked by drug challenges

‘Ticking time bomb’ of global neurodegenerative disease burden will be difficult to defuse

http://www.rsc.org/chemistryworld/2014/07/asd

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