AUTHOR OF THIS BLOG

DR ANTHONY MELVIN CRASTO, WORLDDRUGTRACKER

Microsponges: A novel strategy for drug delivery system

 drug delivery  Comments Off on Microsponges: A novel strategy for drug delivery system
Aug 102014
 

Figure 2 :Reaction vessel for microsponge preparation by liquid- liquid suspension polymerization

Microsponges are polymeric delivery systems composed of porous microspheres. They are tiny sponge-like spherical particles with a large porous surface. Moreover, they may enhance stability, reduce side effects and modify drug release favorably. Microsponge technology has many favorable characteristics, which make it a versatile drug delivery vehicle. Microsponge Systems are based on microscopic, polymer-based microspheres that can suspend or entrap a wide variety of substances, and can then be incorporated into a formulated product such as a gel, cream, liquid or powder. The outer surface is typically porous, allowing a sustained flow of substances out of the sphere. Microsponges are porous, polymeric microspheres that are used mostly for topical use and have recently been used for oral administration. Microsponges are designed to deliver a pharmaceutical active ingredient efficiently at the minimum dose and also to enhance stability, reduce side effects, and modify drug release.

http://www.japtr.org/article.asp?issn=2231-4040;year=2010;volume=1;issue=3;spage=283;epage=290;aulast=Kaity

 


Kaity S, Maiti S, Ghosh AK, Pal D, Ghosh A, Banerjee S. Microsponges: A novel strategy for drug delivery system. J Adv Pharm Technol Res 2010;1:283-90

 


Kaity S, Maiti S, Ghosh AK, Pal D, Ghosh A, Banerjee S. Microsponges: A novel strategy for drug delivery system. J Adv Pharm Technol Res [serial online] 2010 [cited 2014 Aug 10];1:283-90. Available from: http://www.japtr.org/text.asp?2010/1/3/283/72416

 

Figure 3 :Preparation of microsponges by the quasi-emulsion solvent diffusion method

 

 

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