AUTHOR OF THIS BLOG

DR ANTHONY MELVIN CRASTO, WORLDDRUGTRACKER

A pot-economical and diastereoselective synthesis involving catalyst-free click reaction for fused-triazolobenzodiazepines

 PROCESS, SYNTHESIS  Comments Off on A pot-economical and diastereoselective synthesis involving catalyst-free click reaction for fused-triazolobenzodiazepines
Mar 212016
 

 

Green Chem., 2016, Advance Article
DOI: 10.1039/C6GC00497K, Communication
Xiaofeng Zhang, Sanjun Zhi, Wei Wang, Shuai Liu, Jerry P. Jasinski, Wei Zhang
A pot-economical synthesis involving two [3 + 2] cycloadditions for diastereoselective synthesis of novel triazolobenzodiazepine-containing polycyclic compounds

http://pubs.rsc.org/en/Content/ArticleLanding/2016/GC/C6GC00497K?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+rss%2FGC+%28RSC+-+Green+Chem.+latest+articles%29#!divAbstract

A pot-economical and diastereoselective synthesis involving catalyst-free click reaction for fused-triazolobenzodiazepines

 *Corresponding authors
aCentre for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, USA
E-mail: wei2.zhang@umb.edu
bJiangsu Key Laboratory for the Chemistry of Low-Dimensional Materials, Huaiyin Normal University, Huaian, PR China
cSchool of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi’an, PR China
dDepartment of Chemistry, Keene State College, Keene, USA
Green Chem., 2016, Advance Article

DOI: 10.1039/C6GC00497K

A pot-economical synthesis involving sequential [3 + 2] cycloadditions of an azomethine ylide and an azide–alkyne (click reaction) has been developed for diastereoselective synthesis of novel triazolobenzodiazepine-containing polycyclic compounds. A new example of catalyst-free click chemistry of non-strained alkynes is also disclosed

str1

 

str1

 

str1

 

str1

 

str1

 

str1

/////A pot-economical, diastereoselective synthesis, catalyst-free click reaction, fused-triazolobenzodiazepines

Share
Follow

Get every new post on this blog delivered to your Inbox.

Join other followers: