An immobilised monolithic iridium hydrogen transfer catalyst has been developed for use in flow based processing. The monolithic construc thas been used for several redox reductions demonstrating excellent recyclability, good turnover numbersand high chemical stability giving negligible metal leaching over extended periods of use.
A FlowSyn Auto-LF system was employed to automatically process a library of 40 aldehydes and ketones.
An immobilised iridium hydrogen transfer catalyst has been developed for use in flow based processing by incorporation of a ligand into a porous polymeric monolithic flow reactor. The monolithic construct has been used for several redox reductions demonstrating excellent recyclability, good turnover numbers and high chemical stability giving negligible metal leaching over extended periods of use.
E-mail: mavirm@hotmail.com
DOI: 10.1039/C4OB02376E
http://pubs.rsc.org/en/content/articlelanding/2015/ob/c4ob02376e#!divAbstract
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